Mechanistic Insight to C–C Bond Formation and Predictive Models for Cascade Reactions among Alcohols on Ca- and Sr-Hydroxyapatites


 T. Moteki and D. W. Flaherty

 ACS Catal., 2016, 6 (7), pp 4170–4183

DOI: 10.1021/acscatal.6b00556

Open access article published under an ACS Author Choice License

The mechanism for coupling reactions among alcohols (i.e., Guerbet chemistry) is still debated. In this work the interpretation of the formation rates of products, in situ spectroscopy of surface intermediates, and evidence from isotope labeling experiments are combined to clarify the mechanism of the ethanol coupling over hydroxyapatite (HAP) catalysts